Donna Hills PHA
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Intrauterine Insemination and Meloxicam
Canine intrauterine insemination and the use of nonsteroidal anti-inflammatory drugs
Differential impact of birth weight and early growth on neonatal mortality in puppies.
Puppy Care
Toltrazuril and Puppies
Toltrazuril treatment of cystoisosporosis in dogs under experimental and field conditions
Parasitology Research, volume 86, pages 797–799 (2000). Cite this article.
Abstract
Coccidia of the genus Cystoisospora cause mild to severe diarrhea in dogs. The effects of toltrazuril treatment on cystoisosporosis were studied under experimental and field conditions. Twenty-four puppies were experimentally infected, each with 4 × 104 oocysts of the Cystoisospora ohioensis group. Three groups of six puppies were treated 3 dpi with 10, 20, or 30 mg/kg body weight of toltrazuril suspension (5%); the remaining six puppies served as non-treated controls. Toltrazuril suspension or microgranulate was given once in a dose of 10 or 20 mg/kg body weight, respectively, to naturally infected puppies in conventional dog breeding facilities, depending on the coproscopical evidence of infection. Oocyst excretion and clinical data were recorded. Under experimental conditions, the non-treated puppies excreted oocysts beginning at 6 dpi and suffered from catarrhalic to hemorrhagic diarrhea. On 12 dpi, four of six non-treated puppies died. Irrespective of the dose, toltrazuril treatment totally suppressed oocyst excretion, and no diarrhea or other signs of disease were observed in the treated groups. Natural Cystoisospora infections were regularly found during the 3rd or 4th week of age in dog breeding facilities, although not always associated with diarrhea. A single oral application of toltrazuril abrogated oocyst shedding, and the treated puppies remained generally coproscopically negative during the following 2–4 weeks. Cystoisospora is pathogenic for puppies and can induce severe disease. Natural infections are common in conventional dog breeding facilities. Toltrazuril treatment is suitable for controlling cystoisosporosis under experimental and field conditions. A single oral treatment for puppies in the 3rd or 4th week of age is recommended.
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Author Information
Affiliations
Institut für Parasitologie, Bünteweg 17, 30539 Hannover, Germany, DE
A. Daugschies
Bayer AG, 51368 Leverkusen, Germany, DE
H.-C. Mundt
University of Veterinary Medicine, Komenskeho 73, 04001 Kosice, Slovak Republic
Valeria Letkova
Additional Information
Received: 2 February 2000 / Accepted: 4 February 2000
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Toltrazuril Dosing Chart
Toltrazuril Dosage Chart for Puppies
Toltrazuril Dosage Chart
Puppy Weight Prevention Treatment
Based on 5% solution
Note: Keypoint #1 is paramount to your treatment protocol
- 1 lb (16 oz.) 0.1 mL (5 mg/lb, one dose) 0.3 mL (15 mg/lb, one dose per day for 3 days)
- 1.5 lb (24 oz.) 0.15 mL (5 mg/lb, one dose) 0.45 mL (15 mg/lb, one dose per day for 3 days)
- 2 lb (32 oz.) 0.2 mL (5 mg/lb, one dose) 0.6 mL (15 mg/lb, one dose per day for 3 days)
- 2.5 lb (40 oz.) 0.25 mL (5 mg/lb, one dose) 0.75 mL (15 mg/lb, one dose per day for 3 days)
- 3 lb (48 oz.) 0.3 mL (5 mg/lb, one dose) 0.9 mL (15 mg/lb, one dose per day for 3 days)
- 3.5 lb (56 oz.) 0.35 mL (5 mg/lb, one dose) 1.05 mL (15 mg/lb, one dose per day for 3 days)
- 4 lb (64 oz.) 0.4 mL (5 mg/lb, one dose) 1.2 mL (15 mg/lb, one dose per day for 3 days)
- 4.5 lb (72 oz.) 0.45 mL (5 mg/lb, one dose) 1.35 mL (15 mg/lb, one dose per day for 3 days)
- 5 lb (80 oz.) 0.5 mL (5 mg/lb, one dose) 1.5 mL (15 mg/lb, one dose per day for 3 days)
- 5.5 lb (88 oz.) 0.55 mL (5 mg/lb, one dose) 1.65 mL (15 mg/lb, one dose per day for 3 days)
- 6 lb (96 oz.) 0.6 mL (5 mg/lb, one dose) 1.8 mL (15 mg/lb, one dose per day for 3 days)
- 6.5 lb (104 oz.) 0.65 mL (5 mg/lb, one dose) 1.95 mL (15 mg/lb, one dose per day for 3 days)
- 7 lb (112 oz.) 0.7 mL (5 mg/lb, one dose) 2.1 mL (15 mg/lb, one dose per day for 3 days)
- 7.5 lb (120 oz.) 0.75 mL (5 mg/lb, one dose) 2.25 mL (15 mg/lb, one dose per day for 3 days)
- 8 lb (128 oz.) 0.8 mL (5 mg/lb, one dose) 2.4 mL (15 mg/lb, one dose per day for 3 days)
- 8.5 lb (136 oz.) 0.85 mL (5 mg/lb, one dose) 2.55 mL (15 mg/lb, one dose per day for 3 days)
- 9 lb (144 oz.) 0.9 mL (5 mg/lb, one dose) 2.7 mL (15 mg/lb, one dose per day for 3 days)
- 9.5 lb (152 oz.) 0.95 mL (5 mg/lb, one dose) 2.85 mL (15 mg/lb, one dose per day for 3 days)
- 10 lb (160 oz.) 1 mL (5 mg/lb, one dose) 3 mL (15 mg/lb, one dose per day for 3 days)
Understanding Toltrazuril Dosage for Puppies
The toltrazuril dosage chart provided above outlines the recommended amounts for both prevention and treatment of coccidiosis in puppies. This medication plays a vital role in controlling parasitic infections by disrupting the lifecycle of coccidia.
Dosage Guidelines
A common guideline for toltrazuril is approximately 20 mg per kilogram (9 mg per pound) of body weight. The exact dosage can vary based on the concentration of the toltrazuril product used. Always refer to the specific product instructions or your veterinarian’s advice for the most accurate dosing information.
Key Points to Follow
Consult With a Veterinarian: Before starting any treatment, consult with a veterinarian who will evaluate your puppy’s health, age, and weight to provide an accurate dosage recommendation.
Follow Product Instructions: Use the Toltrazuril product as directed on the label. Different products may have varying concentrations, so it’s essential to use the correct volume as specified.
Administer as Directed: Give the medication exactly as instructed by your veterinarian. Do not adjust the dosage without professional guidance to ensure effectiveness and avoid potential side effects.
Importance of Accurate Dosage
Accurate dosing is critical for the safety and efficacy of toltrazuril treatment. Incorrect dosages can lead to ineffective treatment or adverse effects. Always adhere to the recommended dosage guidelines and consult your veterinarian for any concerns.
Conclusion
For the best outcomes in treating and preventing coccidiosis in puppies, use the toltrazuril dosage chart provided above to guide your administration of the 5% liquid suspension. Remember, accurate dosing and veterinary guidance are crucial for your puppy’s health and recovery.
For more information or to purchase toltrazuril, visit Toltrazurilshop.com.
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